College Football Odds, Lines, Week 13 Schedule: Ohio State, USC open as home favorites in rivalry games

Everyone in college football has been circling The Game since Ohio State lost to Michigan last season to determine a berth in the college football playoffs. Heading into Week 13, the matchup could get even bigger than expected – but Vegas has a clear favorite.

Across the board, USC, Oregon and LSU are trying to keep backdoor college football playoff hopes alive with competitive rivalry games. The AAC and Sun Belt also have battles that could decide the seeding and hosting of championship games.

There are five matches between teams that were placed in the College Football Playoff rankings last week. Here are some of the most interesting opening sets for the upcoming week 13 matchups.

All odds courtesy of Caesars Sportsbook.

Michigan in the state of Ohio (-8.5): The Game really is college football’s game of the year, as many expected, but bookmakers in Vegas are pessimistic about their competitiveness. Ohio State has won all of its games by double digits, but that included a scoop-and-score with seconds remaining against Maryland to skew the numbers. Michigan fought Illinois for the first time. Neither team played against an elite opponent, so there’s no telling what might happen.

Notre Dame at USC (-6): The Trojans are looking to wrap up a CFP-caliber regular season with a tricky game against Notre Dame. The Fighting Irish were huge hitters, defeating Clemson, North Carolina and Syracuse over the course of the season. However, USC is playing its best football at the right time. The key will be to avoid a lookahead spot.

Oregon (-3.5) in the state of Oregon: The Ducks are playing their third straight hyper-competitive game after surviving the No. 10 in Utah on Saturday. Oregon State has lost 12 of the last 14 matchups between those two teams, but the Beavers are putting together their best season in a decade. The Beavers rank in the top 30 in goal defense and will play a tied Bo Nix in Oregon in a bitter home rivalry game.

NC State in North Carolina (-6.5) on Friday: The wolfpack is falling apart after losing quarterback Devin Leary to a season-ending injury, while North Carolina hopes to build some momentum as they enter their first ACC championship game since 2015. The Tar Heels lost a heartthrob to Georgia Tech to be sidelined from the CFP talk, but quarterback Drake Maye will face one of his biggest tests yet. This is a rematch game after North Carolina State defeated UNC 34-30 to end last season. Expect the Tar Heels to take full advantage.

Tulane in Cincinnati (-3) on Friday: This game could decide a spot in the AAC championship game — and maybe New Year’s six spots. Tulane demolished a dynamic SMU team and rushes to the finish line. However, Cincinnati is still the two-time defending AAC champion, and while the biggest game of the weekend is in Michigan, that could be next in Ohio.

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